Human beings stand upright, have the faculty of language and a superior mind when compared to other animals. Our frontier begins where our most precious endowment ends: intelligence. We excel at manipulating matter. We can build machines that build machines. The systematic application of our skills is overwhelming, as both the industrial and digital revolution testify. Science is their sovereign representative. Necessary as it was, I argue that reason crumples insufficient now. Frontiers do not call for refinements. To truly overcome our curb as a species, a transformation of our mind is required. I advocate for the need (and possibility) of a difference in kind, not degree, in the way we see reality. Why is this crucial? Nature manifests as an evolutionary process: matter gave way to life in it; then life entrusted its creative pursue to instinct and intelligence. And here we are, at the summit of the complexity gradient, with a nervous system that seems to hide more than we want to acknowledge and less than we are ready to accept. I believe that the decisive frontier is that which defines -and by the same token constrains- who we are. We must face this question: what will supersede mankind? We went to the moon, built particle accelerators, controlled neural activity. Yet little do we know about who we are. What empowered us, is now retarding our evolution. How can we address such a monumental adventure? My proposal is threefold: it needs to be a courageous, collective and conscious endeavor. Courageous as we spearhead it, with the willingness to find what is there to be found, not what we allowed in the first place. Collective beyond a one-man war; with true debate, collaboration and even communion. Finally, and unprecedented in the history of the universe, the effort to evolve can recruit consciousness. Frontiers are provinces where the unknown rests. Perhaps, after all, pushed by our survival instinct, our desire for immortality might not be an impossible feat.